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Unclog pores, reduce excess oil, and clear blemishes with this heavy-hitting ingredient.

Person testing Benzoyl Peroxide products

Byrdie

If you prefer a cleanser, we recommend theDifferin Daily Deep Cleanser.

First, it inhibits the growth of P. acnes, the bacteria that causes acne, explains Chicago dermatologistDr.

Jordan Carqueville, M.D.

Amazon La Roche-Posay Effaclar Duo

PHOTO: Amazon

This trio of attributes makes it ideal for those with inflammatory acnered, painful bumps and blemishes.

The other nice thing?

BPO, as its often called, comes in various formulas and products, from cleansers to creams.

Closeup of La Roche-Posay Effaclar Duo on back of hand with marble countertop in background

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After consulting dermatologists and considering dozens of options, we landed on these top-rated picks.

It can also be used all over the face and solely on pimples that pop up.

Keyaira, tester:“This formula was effective for long-term results.

Differin Daily Deep Cleanser

PHOTO: Amazon

I noticed an improvement with consistent usage of the product.

It did not help overcome huge breakouts but it did help to calm down little flare-ups.”

The featherweight lotion dries clear and matte and can be used on either face and/or body.

A before and after photo showing the impact of using Differin Daily Deep Cleanser

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Thats why we appreciate this formula, specially formulated to be ultra-gentle on skin.

It pairs 10% benzoyl peroxide with popular blemish-fighterstea tree oilandwillow bark, working toshrink your zitquickly.

As far as were concerned, a spot treatment should always make yourtravel bag.

Neutrogena Clear Pore Cleanser/Mask

PHOTO: Amazon

Best Splurge

Obagi CLENZIderm M.D.

And yes, moisturizing is crucial for every skin typeeven acne-prone!

Use it once daily, topping it withsunscreenif youre applying it in the a.m.

Before and after photos showing the effects of using the Neutrogena Clear Pore Cleanser/Mask

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Some reviewers note it can be drying (as many benzoyl peroxide-infused formulas can be!

), so you may want to use this product sparingly until you see how your skin reacts.

There are also ceramides to minimize water loss and further keep skin hydrated.

PanOxyl Acne Foaming Wash

PHOTO: Amazon

Alongside 5% benzoyl peroxide isglycolic acid, willow bark extract, and niacinamide to banish blemishes for good.

Neutrogenas Stubborn Acne line takes the guesswork out of the equation.

According to the brand, it can help reduce blemish redness and size in about four hours.

Photos of person’s back before and after using PanOxyl Acne Foaming Wash

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Enter: Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser.

The daily cleanser also offers a shine-reducing perk, soaking up excess oil with the help ofzinc.

(FYI, dryness can make fine lines and wrinkles more apparent.)

Paula’s Choice CLEAR Regular Strength Daily Skin Clearing Treatment

PHOTO: Amazon

While testing them, we rated them on the following factors:

“Benzoyl peroxide is an antibacterial agent.

Arielle Nagler, M.D.

“It also helps to prevent small pimples calledcomedones.”

CeraVe Acne Foaming Cream Cleanser

PHOTO: Amazon

Regular use may even help preventacne scarsfrom forming.

you might typically use benzoyl peroxide as often as twice daily.

But if youre applying it during the day, Dr. Nagler advises pairing it with a strong SPF.

DermaQuest DermaClear Spot Treatment

PHOTO: Dermstore

Starting small and working your way up to multiple uses daily is always a good idea, too.

Melanie reviewed testing insights from Byrdies lab to help create the list of top picks.

Yang Z, Zhang Y, Lazic Mosler E, et al.Topical benzoyl peroxide for acne.Cochrane Database Syst Rev.

Obagi CLENZIderm M.D. Therapeutic Lotion

PHOTO: Amazon

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doi:10.1002/14651858.CD011154.pub2

Levin J, Momin SB.How much do we really know about our favorite cosmeceutical ingredients?.

J Clin Aesthet Dermatol.

Avene Cleanance ACNE Medicated Clearing Treatment

PHOTO: Avene

2010;3(2):22-41.

2020;34(S5):15-20.

Yang Z, Zhang Y, Lazic Mosler E, et al.Topical benzoyl peroxide for acne.

Clean & Clear PERSA-GEL10 Acne Medication

PHOTO: Amazon

Cochrane Database Syst Rev.

2020;3(3):CD011154.

Clin Cosmet Investig Dermatol.

Kate Somerville Anti Bac Acne Clearing Lotion

PHOTO: Amazon

2003;14(3):153-157.

2013;12(5):542-545.

1986 Dec;25(10):664-7. doi: 10.1111/j.1365-4362.1986.tb04534.x.

Urban Skin Rx Clear Complexion Acne Serum + Spot Treatment

PHOTO: Ulta

Am J Clin Dermatol.

2018 Apr;19(2):275-286. doi: 10.1007/s40257-018-0352-y.

PMID: 29549588; PMCID: PMC5978908.

Neutrogena Stubborn Acne AM Treatment

PHOTO: Amazon

Am J Clin Dermatol.

2008;9(3):193-204. doi: 10.2165/00128071-200809030-00010.

Matin T, Goodman MB.Benzoyl peroxide.

Cetaphil Gentle Clear Complexion-Clearing BPO Acne Cleanser

PHOTO: Amazon

StatPearls Publishing; 2024.

Rodan+Fields: UNBLEMISH Dual Intensive Acne Treatment

PHOTO: Rodan+Fields

Person rubbing Differin Daily Deep Cleanser onto cheek with white shower curtain in background

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